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Objective To study the relationship between carotid atherosclerosis (CAS) and serum markers in elderly essential hypertension (EH) patients.Methods Three hundred and eightyeight elderly EH patients who underwent carotid colour ultrasonography and biochemical testing served as an EH group and 82 subjects undergoing physical examination served as a control group.The patients in EH group were divided into plaque-free group (n =142),stable plaque group (n=132),and unstable plaque group (n=114).The relationship between CAS and serum FPG,Hcy,TBIL,DBIL,IBIL,UA,ferritin,fibrinogen,CRP levels was analyzed.Results The incidence of CAS and serum Hcy level were significantly higher in EH group than in control group (63.40％ vs 31.71％,12.69±3.58 μmol/L vs 6.96±2.89 μmol/L,P＜0.01).The incidence of CAS was 63.40％ in EH patients.The serum levels of FPG,TC,TG,LDL-C,Hcy,UA,ferritin,fibrinogen,CRP were significantly higher while those of TBIL,DBIL,and IBIL were significantly lower in stable plaque group than in unstable plaque group (P＜0.05,P＜0.01).Logistic regression analysis showed that stable CAS was negatively related with serum levels of TBIL and IBIL and positively related with those of FPG,TC,LDL-C,Hcy,UA,ferritin,fibrinogen and CRP,history of smoking,incidence of DM and hypertension (P＜0.05).Conclusion Serum levels of TBIL and IBIL are the protective factor for CAS while those of FPG,Hcy,UA,ferritin,fibrinogen and CRP are the risk factors for CAS in elderly EH patients.
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Objective To analyze the epidemiological characteristics of morning hypertension in people with eseential hypertension in Dali Bai autonomous prefecture,and to study the management model for morning hypertension. Methods From May 2015 to January 2017,302 patients with hypertension in the People's Hospital of Dali Bai Autonomous Prefecture were divided voluntarily into two groups,including single management group (group 1)and systematic management group (group 2 ).During six to twelve months follow －up,the changes in control rate of morning hypertension,serum biochemical indicators,KAP and Mofisky score were observed before and after intervention. Results The proportion of morning hypertension in people with hypertension was 62.25%,61.11% in men and 62.86%in females.The patients with morning hypertension had higher age,BMI,WC,TC,LDL－C,SBP,DBP,CRP, FBG,SCr,Sokolow－Lyon,Cornell,LVMI,UACR and MAU,more cervical plaque,and lower HDL －C and eGFR compared with non－morning hypertension(P＜0.05 －0.001).The number of patients with target organ damage was most in patients with morning hypertension by home blood pressure monitoring(HBPM),second in ambulatory blood pressure monitoring(ABPM),least in clinic blood pressure monitoring (CBPM)(P＜0.05 －0.001).After six to twelve months follow－up,compared with before intervention,the control rate of morning hypertension was increased (43.78%vs.61.39%),and SBP,DBP,HR,BMI,WC,TC,TG,UA,Scr were decreased in both two groups,which in the group 2 were lower than those in the group 1(P＜0.05 ).Compared with before intervention,the KAP score and Mofisky in the two groups after intervention were significantly improved(P＜0.05－0.01)[K score:(9.63 ±3.01)points vs.(14.26 ±2.89)points in the group 1,(10.11±2.34)points vs.(17.23 ±1.06)points in the group2;A score:(2.05 ±1.21)points vs.(2.98 ±0.25)points in the group 1,(2.08 ±1.65)points vs.(3.56 ±0.42)points in the group 2,P score:(4.39 ±2.36)points vs.(5.89 ±3.24)points in the group 1,(4.71±3.42)points vs.(7.26 ± 1.21)points in the group 2,Mofisky questionnaire score:(61.23 ±5.79)points vs.(72.36 ±6.18)points in the group 1,(60.89 ±6.47)points vs.(88.45 ±5.48)points in the group 2],which in the group 2 were higher than those in the group 1(P＜0.01).Conclusion The control rate of morning hypertension in patients with hypertension in Dali Bai autonomous prefecture is low,the HBPM is better way to predict the target organ damage,and systematic management model is effective to improve the control rate of morning hypertension and so do in KAP and Morisky score.
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Objective To investigate the relationship between metabolic syndrome ( MS) and non-alcoholic fatty liver disease(NAFLD),to find risk factors of NAFLD and provide references for the prevention of NAFLD in patients with MS.Methods 1024 patients were enrolled, and the patients were divided into the non -NAFLD group,NAFLD group and NAFLD+MS group based on the physical examination outcomes .All the patients received abdominal ultrasound and blood biochemical examination ,and the relationship between MS and NAFLD was analyzed .Results (1)The proportion of NAFLD was 21.39%(219/1024),which of males was higher than that of females (30.26%vs.11.41%,χ2 =26.35,P<0.01).The proportion of MS was 35.55%(364/1024),the proportion of NAFLD in the MS group was higher than that in the non -MS group(40.66%vs.10.76%,χ2 =38.16,P<0.001) .With the increase of MS examination items,the proportion of NAFDL was increased (χ2 =221.13,P<0.001).(2) Compared with the non-NAFLD group,the levels of BMI,WC,TG,TC,LDL-C,ALT,UA,SBP,DBP,CRP,FBG, FP,MAU,Fg in the NAFLD group and NAFLD +MS group were higher , and the level of HDL -C in the NAFLD group and NAFLD+MS group was lower (P<0.01-0.001).The result of logistic regression analysis showed that WC,BMI,high TG,high UA were independent risk facts for the prevalence of NAFLD .Conclusion There is close association between NAFLD and MS ,and WC,BMI,TG,SUA are risk factors of NAFLD.
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Objective To study the application of remifentanil combined with sevoflurane or propofol in the anesthesia of patients with intracranial tumors.Methods From January 2015 to December 2015,60 patients with intracranial tumor surgery in our hospital were selected as the research object in this study.They were randomly divided into A group and B group,each group had a total of 30 cases.Patients in group A were treated with remifentanil combined with sevoflurane anesthesia,and B group was treated with remifentanil and propofol anesthesia.Comparative analysis of A group and B group of patients with clinical indicators.Results During the operation,two groups of patients with end tidal carbon dioxide partial pressure and pulse oxygen saturation score.Two groups of patients in the immediate intubation heart rate and blood pressure were significantly lower than before anesthesia,A group reduced the degree of greater,with statistical difference(P<0.05).In group A,30 min and 1H were significantly higher than those in group B after anesthesia,and the difference was statistically significant(P<0.05).The anesthesia time of A group was(187.3±22.7)min,and the extubation time was(22.1±8.2)min.The anesthesia time of B group was(181.4±19.1)min,and the extubation time was(10.2±5.3)min.As a result,B group of patients with anesthesia time and extubation time were significantly less than the A group,and with statistical difference(P<0.05).Conclusion Remifentanil Combined with propofol and sevoflurane anesthesia in patients with intracranial tumors compared to two kinds of methods can effectively stabilize the patient's life signs,but remifentanil and propofol recovery time is fast,contribute to the balance of cerebral oxygen supply and consumption in a certain extent,with the further promotion and application of clinical significance.
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The paper analyzes different expressions of indirectly associated strong-weak connection in the process of biomedical literature knowledge discovery,defines the effect and function of strong-weak connection on literature knowledge discovery,and indicates that the accuracy rate of the discovery of potential connection through strong connection is obviously higher than the accuracy rate obtained through weak connection,and strong connection can serve as an important factor for improving the application effect of literature knowledge discovery.
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Objective:To learn the cognition and attitudes of psychometric ethics of graduate students whose major was clinical psychology or counseling psychology,and to investigate whether ethics training could influence their cognition and attitude.Methods:Researchers distributed the questionnaire online regarding cognition and attitudes of psychometric ethics among clinical and counseling psychology graduate students.Seventy-six feedbacks were collected (4 students were learning ethics courses,27 students had learned ethics courses,45 students hadnt learned ethics courses).The questionnaire included the Psychometric Cognition Questionnaire (PCQ),Situational Judgement Questionnaire (SJQ) and Psychometric Attitude Questionnaire (PAQ).The first two sets of questionnaires reflected ethics knowledge.The last one showed ethics attitudes and behavioral tendencies.Results:The correct rates in participants who had learned or were learning ethics were 76.5％ and 75.1％ at the first and second set of questionnaires,while were 73.9％ and 74.2％ in other participants.The correct rates of three major clauses in PCQ were 90.3％,67.7％ and 74.2％,significantly higher than participants who never learned ethics,whose correct rates were 88.9％,66.7％,and 44.4％ (Ps ＜ 0.05).There were no significant differences in SJQ between those who had learned or was learning ethics and those who had never learned ethics (Ps ＞0.05).Participants who had learned or were leaning ethics scored in sum in PAQ that had no significant differences with those who had never learned ethics(Ps ＞ 0.05).Conclusion:Clinical and counseling psychology graduate students master considerable level of knowledge on ethics and attitude.Ethics training is essential for acquiring psychometric ethics.
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Objective To compare the prevalence and clinical charecteristics of metabolic syndrome(MS) in aged people of Dali Bai Autonomous Prefecture under three diagnostic criteria.Methods A total of 1 386 patients in outpatient department or admitted to our hospital were recruited.The different prevalences under the World Health Organization(WHO) in 1999,the China Diabetes Society in 2004 (CDS 2004) and the China Diabetes Society in 2013(CDS 2013) definitions respectively were calculated and the results were compared by κ test.Results The prevalences of metabolic syndrome under WHO,CDS2004,and CDS2013 were 30.38％,33.77％ and 36.87％,respectively,it increased with age,and was most highest in ＞ 70～ 80 years aged group (P ＜ 0.05-0.01),the number of hypertension abnormality was more than 60.00％,and the most combination of abnormalities ＞ 3 in MS was hypertension + hyperglycemia + obesity (P ＜ 0.01);The 92.86％ concordance of MS cases was found between CDS2004 and CDS2013,90.19％ between WHO and CDS2013,and 80.23％ between WHO and CDS2013 (P ＜ 0.05-0.01).Conclusion The prevalence of MS increased with age in eldely people of Dali Bai Autonomous Prefecture,there is different between man and female,hypertension is the common abnormality in components of MS.The agreement among three criterias is relatively high,and the prevalence of MS has high level by CDS2013.
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Objective To investigate the status and clinical and epidemiological characteristics of human metapneumovirus (hMPV) and human bocavirus (HBoV) infections in children with acute respiratory tract infections (ARTIs) in Taiyuan. Methods A total of 549 children with ARTIs from November 2012 to May 2013 and November 2013 to May 2014 were recruited. The pharyngeal swab specimens were collected. The hMPV and HBoV were detected by using real-time PCR. Results In 549 children, 56 children (10.2%) were hMPV positive on swab specimens, 15 children (2.7%) were HBoV positive on swab specimens. The detection rates of hMPV and HBoV in November 2012 to May 2013 were 12.3%and 2.0%, respectively, and in November 2013 to May 2014 were 6.5%and 4.0%, respectively. The detection rate of hMPV was signiifcantly different between two periods (P<0.05), while the detection rate of HBoV has no signiifcant difference between two periods. In different months, the detection rate of hMPV and HBoV showed no signiifcant difference. The highest detection rates of hMPV and HBoV were all in children younger than two years old. The highest detection rate of hMPV was in children with asthmatic bronchitis or bronchiolitis. Conclusion In Taiyuan, during the monitoring periods, the ARITS are associated with childhood hMPV and HBoV infection especially in infants and toddlers. hMPV is one of the most important pathogens in infants and toddlers with wheezing.
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Objective:To use pivot tables will pay the most valuable information in the table, add, reduce staff this month, and does not increase don't decreases but the amount of personnel data extract and work department is changed.Methods: Use pivot table to find differences, by adding auxiliary column identifier (1,-1) to solve the existing in the personnel salary is different.Results:Dynamic understanding of the inflows and outflows of hospital employees, in order to grasp the change situation of hospital human resource cost.Conclusion: It saves the human, fast and convenient, improves the work efficiency and accuracy.
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Objective Use real-time fluorescence quantitative polymerase chain reaction(PCR)to determine HBV DNA,then calculate the linear range and the minimum detection limit,which are the main performance indicators in the laboratory verification. Methods According to the related documents,by serial dilution of high concentration samples,samples of serial concentrations were obtained which were out of the linear range mentioned in the instructions,then verifid the new linear range.By serial dilution of low concentration,samples were obtained,the concentrations of which were lower than the minimum detection limit of provide by the manufacturer,then the new minimum detection limit was verified.Results The linear range of HBV DNA detection was 8.58× 102 -8.41×107 IU/mL,and the minimum detection limit of HBV DNA detection was 4.07 ×102 IU/mL.Conclusion The linear range and the minimum detection limit of Real-time fluorescence quantitative PCR assessed reaches the expected requirement,and the method and validation scheme are simple and feasible.
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Currently, organ transplantation is the most efficient treatment for some terminal stage diseases. However, organ transplantation surgery may induce great psychological changes before and after surgery, which may induce certain psychological features. As a special group, college students have varying physiological and psychological features from general groups. To date, there have been few studies on psychological features and intervention for college students undergoing organ transplantation. This paper aimed to discuss these issues.
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OBJECTIVE To monitor hospital infection continuously in five years in order to learn the rule of dynamic movements and its characters.METHODS To analyze the documents by prospective monitoring and retrospective(investigation).RESULTS The number of discharged inpatients increased year by year while the infection rate(developed) smoothly.Its average rate was 6.88%.CONCLUSIONS The aim to take hospital infection under control has(accomplished).